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SMITHKLINE BEECHAM, the pharmaceutical giant, is heading into a “phenomenal” growth cycle similar to that before the 1994 demise of its blockbuster ulcer drug Tagamet, its chief executive said yesterday.

In an interview to mark the 10th anniversary of the group’s formation later this month, Jan Leschly said investors would see the first fruits of the group’s early move into genomics going into human trials later this year and next.

But Mr Leschly said the roll out of its diabetes treatment Avandia, new indications for its anti-depressant Paxil/Seroxat and a potential doubling of vaccine sales over the next four to five years were already putting the group on a new plane.

Annual sales of GlaxoSmith-Kline’s Avandia could rise by a half, analysts said yesterday after news that the blockbuster diabetes drug could also be used to prevent Type II diabetics developing.

In the largest diabetes-prevention trial ever conducted, Avandia was found to cut the risk of developing diabetes by 62 per cent. The results of the landmark study were reported yesterday in The Lancet and at the annual meeting of the European Association for the Study of Diabetes.

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